PREVENTING CERVICAL CANCER

January is National Cervical Cancer Awareness Month

One of the great success stories in cancer research, since annual Pap test cervical cancer screenings were introduced in the 1950s, cases of what was once the number one cancer in women have plummeted. Human Papillovirus (HPV) vaccination has further reduced the numbers.

“Today, we know cervical cancer can be prevented with proper screening to find pre-cancers before they develop into invasive cancer,” said Stanley Santiago, M.D., an Obstetrics & Gynecology physician at Keys Medical Group. “If a pre-cancer is found, it can be treated, stopping cervical cancer before it really starts.”

One factor in cervical cancer is the prevalence of the human papilloma virus (HPV) in society. An estimated 80% of sexually active women will become infected with the virus at some point, but of the more than 100 strains of HPV identified, only a few high-risk strains are connected to cervical cancer. The vast majority of HPV infections resolve without any treatment or intervention.

The Centers for Disease Control and Prevention recommends young women and men receive HPV vaccination at 11 or 12 years of age to provide the best protection long before the start of any sexual activity. Catch-up vaccines are recommended for males through age 21 and for females through 26 years of age. In females, vaccination helps protect against two types of HPV that cause 70 percent of cervical cancer cases.

“Unfortunately, the CDC reports more than 4,000 U.S. women still die from cervical cancer every year,” said Dr. Santiago. “Women at risk of dying from the disease today are those who have been screened infrequently – or not at all. All women should begin cervical cancer screening via a Pap test at age 21 and women between the ages of 21 and 29 should have a Pap test at least every three years. HPV testing should be done only if needed after an abnormal Pap test.”

Recently, changing guidelines about screening frequency have created confusion. What used to be a clear direction from the American Cancer Society – “get a yearly Pap test” – has become less clear. Recommended time between screenings is now longer, and two separate tests are available.

While not all physicians agree on the new guidelines, following are good rules from the American Congress of Obstetricians and Gynecologists and the American Cancer Society to protect yourself against cervical cancer. Be proactive in discussing with your doctor whether these screening guidelines are right for you.

  • Women between the ages of 30 and 65 should have both a Pap test and an HPV test at least every five years.
  • Women over 65 who have had regular screenings with normal results should not be screened for cervical cancer.
  • Women who are at increased risk for cervical cancer may need to increase the frequency of these screenings. Notably, African American and Hispanic women have a higher incidence of cervical cancer than other ethnic groups.
  • Over 120 HPV genotypes, only 40 are sexually transmitted and only 13 genotypes have been demonstrated to cause cervical cancer.
  • Quadrivalent vaccine (HPV 6, 11, 16, 18) and bivalent vaccine (HPV 16 and 18)  has been approved for girls starting vaccination at 9 to 26 years old.
  • Only the Quadrivalent has been approved for young men.
  • A new vaccine that protects against 9 genotypes has been approved by the FDA (HPV 6, 11, 16. 18, 31, 33, 45, 52 and 58).
  • All vaccines confer nearly 100% protection against high-grade CIN caused by HPV types.
  • Quadrivalent also protects against lower genital warts.
  • The vaccine is composed of a 3 dose series. The second dose is administered 1-2 months after the first, and the third dose should be administered 6 months after the first.
  • If the dosing schedule is interrupted, the series does not need to be restarted.
  • No HPV testing is required or recommended prior to vaccination.
  • Women who had a hysterectomy for benign conditions don’t need to be screened for cervical cancer with a pap smear.

In short, the American Cancer Society no longer recommends getting a Pap test every year, because it generally takes longer than that (10-20 years) for cervical cancer to develop. As the debate continues, there is also the option to have a separate test for HPV alone. Again, discuss with your doctor the appropriate actions based on your age, lifestyle and risk factors.

To find a physician or learn more about taking care of your health, visit LKMC.com or call (305) 292-DOCS.

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